Process to Obtain a Trifluoromethylating Composition

A cuprating reagent of formula I and polymers or oligomers thereof:

• Cu is in the oxidation state of +1;
• M is lithium, sodium, potassium, rubidium, cesium, calcium, barium or magnesium;
• S is N,N-dimethylformamide (DMF), 1,3-dimethyl-2-imidazolidinone (DMI), N,N-dimethylacetamide (DMAC), 1,3-dimethyl-3,4,5,6-tetrahydro-2(1H)-pyrimidinone (DMPU), N-methylpyrrolidone (NMP), dimethylsulfoxide (DMSO), tetramethylurea (TMU), and hexamethylphosphoramide (HMPA);
• R1 is C1-C20 alkyl or C5-C7 aryl, wherein C1-C20 alkyl is optionally substituted with one or more C5-C7 aryl, C1-C20 alkoxy or C5-C7 aryloxy and wherein C5-C7 aryl is optionally substituted with one or more C1-C20 alkyl, C1-C20 alkoxy, C5-C7 aryl and C5-C7 aryloxy;
• X is chloride, bromide or iodide;
• l is an integer from 1 to 20;
• m is an integer from 0 to 20;
• n is an integer from 1 to 20;
• p is an integer from 2 to 40;
• q is an integer from 0 to 10;
• with the proviso that:
• p is larger than n;
• and
• the sum of l and n is equal to the sum of p and q when M is selected from lithium, sodium, potassium, rubidium and cesium;
• or,
• the sum of n and twice the value of l is equal to the sum of p and q when M is selected from calcium, magnesium and barium;
• and
• with the proviso that the compound of formula I is not LiCu(OCH3)2, Li4Cu4(OC(CH3)3)8, Ba2Cu4(OC(C2H5)3)8, BaCu6(OC(C2H5)3)8, BaCu2(OC(CH3)3)4 or polymers or oligomers thereof, NaCu(OC(CH3)O2, and Na4Cu4(OC(C2H5)3)8 or polymers or oligomers thereof.