Treating patients with intravenous ibuprofen
AssigneeCumberland Pharmaceuticals Inc.
InventorsLeo Pavliv, Amy Dix Rock
Life of this patent
Estimating the term…
Abstract
Methods of treating a patient in need thereof, comprising administering to the critically ill patient an intravenous pharmaceutical composition comprising ibuprofen in an amount effective to treat at least one condition in the patient chosen from pain, inflammation, and fever and to provide a clinically relevant effect on mean arterial pressure of the patients during the dosage interval comprising no increase or no statistically significant increase in mean arterial pressure.
Claims21
A method of treating at least one condition chosen from pain, inflammation, and fever in human patients in need thereof, comprising administering to human patients an intravenous ibuprofen pharmaceutical composition in an amount effective to treat at least one condition of the patients selected from the group consisting of pain, inflammation, and fever, the patients having a mean arterial pressure prior to intravenous administration of the intravenous ibuprofen, such that the mean arterial pressure of the patients does not increase during the dosage interval from a baseline level measured prior to intravenous administration of the ibuprofen.
A method of treating human patients, comprising administering to the patients an intravenous ibuprofen pharmaceutical composition in an amount effective to treat at least one condition chosen from pain, inflammation, fever in the patients and providing no statistically significant increase in mean arterial pressure to said patients.
14-15. (canceled)
(canceled)
A method of treating at least one condition chosen from pain, inflammation, and fever in critically ill patients having increased risk of cardiovascular events, comprising intravenously administering to critically ill patients a dose of an intravenous ibuprofen pharmaceutical composition in an amount effective to treat at least one condition chosen from pain, inflammation, and fever in the critically ill patients, the dose of intravenous ibuprofen providing no statistically significant increase in mean arterial pressure to said patients.
Dependencies are inferred from the claim text.