Treatment using reprogrammed mature adult cells

A method of replenishing desired target cells in a patient suffering from a neurological disease or disorder, wherein the method comprises (i) obtaining committed cells;

• (ii) reprogramming the committed cells by contacting with an antibody that engages a receptor that mediates capture, recognition or presentation of an antigen at the surface of the committed cells to obtain reprogrammed cells, wherein the reprogrammed cells are neuronal stem cells;
• and (iii) administering the neuronal stem cells to the patient whereby the desired target cells in the patient are replenished.

A method of obtaining reprogrammed neuronal stem cells fir administration to a patient in need thereof, wherein the method comprises:

• (i) obtaining committed cells;
• (ii) reprogramming the committed cells by contacting with an antibody that engages a receptor that mediates capture, recognition or presentation of an antigen at the surface of the committed cells to obtain the reprogrammed neuronal stem cells.

A method of preparing a medicament or pharmaceutical composition for administration to a patient suffering from a neurological disease or disorder, wherein the method comprises:

• (i) obtaining committed cells;
• (ii) reprogramming the committed cells by contacting with an antibody that engages a receptor that mediates capture, recognition or presentation of an antigen at the surface of the committed cells to obtain reprogrammed cells, wherein the reprogrammed cells are neuronal stem cells;
• and, (iii) optionally, combining the reprogrammed neuronal stem cells with one or more pharmaceutical excipients.

A method of treating a patient suffering from a neurological disease or disorder, wherein the method comprises:

• (i) obtaining committed cells;
• (ii) reprogramming the committed cells by contacting with an antibody that engages a receptor that mediates capture, recognition or presentation of an antigen at the surface of the committed cells to obtain reprogrammed cells, wherein the reprogrammed cells are neuronal stem cells;
• and (iii) administering the neuronal stem cells to the patient whereby the desired target cells in the patient are replenished.