Compositions and methods for molecular imaging of oxygen metabolism
AssigneeRockland Technimed Ltd.
InventorsPradeep M. Gupte, Robert L. DeLaPaz, Ramanathan Ravichandran
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Abstract
Provided are compositions containing an emulsion containing a perfluorinated compound, as well as methods for preparation of the compositions. Also provided are formulations containing a complex of oxygen-17 and the emulsion compositions. Additionally provided are methods for the preparation of the formulations as well as kits containing the formulations. Further provided are methods of use of the formulations in imaging of tissues using a magnetic resonance imaging system.
Claims41
A composition comprising an emulsion comprising:
- particles of at least one perfluorocarbon;
- and
- at least one emulsifying agent;
- wherein the particles have an average particle size of between about 0.1 μm and about 5 μm.
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A method for producing a composition comprising an emulsion, comprising:
- producing a surfactant dispersion in a water-salt medium;
- and
- homogenizing at least one perfluorocarbon compound in the surfactant dispersion, wherein the resulting composition comprises an emulsion.
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Dependencies are inferred from the claim text.