Oral Enzyme Compositions for Intestinal Delivery
AssigneeHistapharm Inc.
InventorsMircea-Alexandru Mateescu, Carmen Calinescu, Pompilia Ispas-Szabo, Bruno Mondovi, Rodolfo Federico
Life of this patent
Estimating the term…
Abstract
The present disclosure describes compositions for intestinal delivery of enzyme formulations and methods of treating health problems with these formulations. More specifically, the enzyme formulations include at least one histaminase and various methods of treatment of physical conditions, such as inflammation, allergy, histamine intolerance, and intestinal cancer.
Claims55
A gastro-resistant solid dosage form for the oral administration of therapeutic enzymes with intestinal delivery comprising:
- a cationic polymer, an anionic polymer, or a neutral polymer, or a combination thereof;
- and
- at least one enzyme.
An intestinal delivery composition for treating or alleviating intestinal inflammation comprising:
- a therapeutically effective amount of a histaminase enzyme and a catalase enzyme, in association with an acceptable intestinal delivery pharmaceutical formulation comprising at least one excipient as a matrix former.
Dependencies are inferred from the claim text.