Method of providing agents to the cochlea
AssigneeNewSouth Innovations Pty Limited
InventorGary David Housley
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Abstract
Provided is a method of transfecting cells of the cochlea with an agent by electroporation, and in certain embodiments using a cochlear implant to provide at least one electroporation electrode.
Claims14
A method of transfecting cells with an agent by electroporation within a cochlea of a subject, the method comprising introducing a cochlear implant which comprises at least one electrode into the cochlea, providing the agent to the cochlea, and providing at least one second electrode, and then providing an electroporation electric field between the at least one electrode and the at least one second electrode and thereby transfecting cells with the agent.
A cochlear implant, comprising:
- electroporation-driving circuitry and auditory nerve stimulator circuitry such that the chochlear implant can generate both an electroporation mode electrical pulse profile or an auditory nerve stimulator electrical pulse profile, and
- at least one electrode coupled to the electroporation-driving circuitry and auditory nerve stimulator circuitry for providing electroporation and auditory nerve stimulator electrical pulse profiles to the cochlea.
Dependencies are inferred from the claim text.