Compositions and methods for inhibiting expression of tmprss6 gene
AssigneeAlnylam Pharmaceuticals, Inc.
InventorsDavid Bumcrot, Brian Bettencourt, Ivanka Toudjarska
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Abstract
The invention relates to double-stranded ribonucleic acid (dsRNA) compositions targeting the TMPRSS6 gene, and methods of using such dsRNA compositions to inhibit expression of TMPRSS6.
Claims29
A double-stranded ribonucleic acid (dsRNA) for inhibiting expression of TMPRSS6, wherein said dsRNA comprises a sense strand and an antisense strand, the antisense strand comprising a region of complementarity to a TMPRSS6 transcript which comprises at least 15 contiguous nucleotides differing by no more than 3 nucleotides from one of the antisense sequences listed in Tables 2, 3 or 4.
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Dependencies are inferred from the claim text.