Back to results
US 2014/0194479 A1Published application
Compositions and methods for treating mood disorders
OwnerClaudia SCHMAUSS, Amir LEVINEinventors
Life of this patent
Estimating the term…
Loading patent…
Loading patent…
OwnerClaudia SCHMAUSS, Amir LEVINEinventors
Estimating the term…
The present invention provides, inter alia, methods for enhancing the anti-depressant efficacy of a selective serotonin re-uptake inhibitor (SSRI) in a patient being treated for a mood disorder. These methods include administering to a patient in need thereof a therapeutically effective amount of an SSRI and a therapeutically effective amount of a modulator of histone expression. Also provided are methods for identifying a patient population that suffers from a mood disorder that is more likely to respond to SSRI treatment. Further provided are compositions for treating or ameliorating the effects of a mood disorder.
A method for enhancing the anti-depressant efficacy of a selective serotonin re-uptake inhibitor (SSRI) in a patient being treated for a mood disorder, the method comprising administering to a patient in need thereof a therapeutically effective amount of an SSRI and a therapeutically effective amount of a modulator of histone expression.
A method for identifying a patient population that suffers from a mood disorder that is more likely to respond to SSRI treatment comprising:
A composition for treating or ameliorating the effects of a mood disorder comprising an effective amount of an SSRI, an HDACi, and a pharmaceutically acceptable carrier.
A method for preventing, treating or ameliorating the effects of age-related cognitive deficits in a patient with a history of early life stress comprising administering to the patient in need thereof an effective amount of an HDACi.
A composition for preventing, treating or ameliorating the effects of age-related cognitive deficits in a patient with a history of early life stress comprising an effective amount of an HDACi and a pharmaceutically acceptable carrier.
A method for identifying and treating a patient population that suffers from a mood disorder that is more likely to respond to a combination SSRI/HDACi treatment comprising:
Dependencies are inferred from the claim text.