5,6-disubstituted oxindole-derivatives and use thereof for treating vasopressin-dependent diseases

A compound of the formula I

• in which
• R1 and R2 are independently of one another hydrogen, C1-C3-alkyl, C1-C3-fluoroalkyl, C1-C3-alkoxy, C1-C3-fluoroalkoxy, halogen or CN;
• R3 is hydrogen or C1-C4-alkyl;
• R4 is ethoxy, fluorinated ethoxy or isopropoxy;
• R5 is hydrogen or methyl;
• R6 is Br, Cl, F or CN;
• R7 is Cl, F or CN;
• R8 and R9 are independently of one another C1-C3-alkyl or C1-C3-fluoroalkyl;
• X1 is O, NH or CH2;
• X2 and X3 are N or CH, with the proviso that X2 and X3 are not simultaneously N;
• X4 is N or CH;
• a and b are independently of one another 0, 1 or 2;
• and
• m, n, o and p are independently of one another 1, 2 or 3;
• and their pharmaceutically acceptable salts and prodrugs thereof.