Drug screening method
AssigneeNational Chiao Tung University
InventorsJinn-Moon Yang, Kai-Cheng Hsu
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AssigneeNational Chiao Tung University
InventorsJinn-Moon Yang, Kai-Cheng Hsu
Estimating the term…
A drug screening method is disclosed. The drug screening method includes steps of screening a compound library to obtain a first group of compounds capable of binding to a wild type target; screening the first group of compounds to obtain a second group of compounds capable of binding to a mutant site of a mutant target; analyzing characteristics of binding sites of the wild type target and the mutant type target to obtain physico-chemical properties of the binding sites; identifying a candidate from the second group of compounds according to the physico-chemical properties of the binding site; and performing a bio-assay on inhibitory activity of the candidate.
A drug screening method, comprising steps of:
A method of inhibiting neuraminidase, comprising a step of administering to an subject a therapeutically effective amount of a compound of formula (I),
A method of treating influenza, comprising a step of administering to a subject a therapeutically effective amount of a compound of formula (I)
Dependencies are inferred from the claim text.