US 2014/0194367 A1 · AGROCYBE AEGERITA LECTIN AAL-2, AND ENCODING GENE THEREOF, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF

Abstract

The isolated Agrocybe aegerita lectin AAL-2 is able to inhibit the growth of tumor cells by inducing apoptosis. In the animal study, the Agrocybe aegerita lectin AAL-2 has been showed to be capable for tumor therapy. Furthermore, the AAL-2 preferentially binds to the carbohydrate or glycoproteins with its N-Acetylglucosamine, which can be used for diagnosing the N-Acetylglucosamine-associated diseases or detecting N-Acetylglucosamine-modified carbohydrates.

Claims10

Dependent claims

An Agrocybe aegerita lectin AAL-2, characterized by that the amino acid sequence is set forth in (a) or (b):

(a) The amino acid sequence set forth in SEQ ID NO:
2;
or
(b) The derived sequences obtained by the substitution, deletion or/and insertion of one or multiple amino acid residues in the amino acid sequence set forth in SEQ ID NO:
2 that still have the functions of amino acid as set forth in SEQ ID NO:
2.

3 more elements

Dependencies are inferred from the claim text.

Agrocybe aegerita lectin aal-2, and encoding gene thereof, preparation method therefor and application thereof

Life of this patent

Agrocybe aegerita lectin aal-2, and encoding gene thereof, preparation method therefor and application thereof

Life of this patent

Abstract

Claims10