Vault Agents for Treating Chronic Kidney Disease
OwnerSusanne B. Nicholas, Leonard H. Rome +1inventors
InventorsSusanne B. Nicholas, Leonard H. Rome, Valerie A. Kickhoefer
Life of this patent
Estimating the term…
Abstract
The invention relates to compositions of vault complexes containing cell adhesion inhibiting agents, such as a RGD-peptide, and methods of using the vault complexes in the treatment of diseases, such as chronic kidney disease.
Claims25
A vault complex comprising a cell adhesion modifying substance.
A pharmaceutical composition for treating and/or preventing chronic kidney disease in a subject, comprising a cell adhesion modifying substance incorporated within a vault complex, and at least one pharmaceutically acceptable excipient.
A method of treating and/or preventing chronic kidney disease in a subject, comprising administering to the subject an effective amount of a cell adhesion modifying substance incorporated within a vault complex.
Dependencies are inferred from the claim text.