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US 2014/0194358 A1Published application
Prominin-1 peptide fragments and uses thereof
AssigneeChildren's Medical Center Corporation
InventorsAvner Adini, Robert D'Amato
Life of this patent
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Abstract
Described herein are peptide compositions of a prominin-1, which have regenerative activity. As such the peptides are useful when regeneration is needed, for example, to enhance angiogenesis, increase VEGF binding to endothelial cells, promote vasodilation, enhance cell migration, enhance cell proliferation, stimulate neuronal growth, prevent neurodegeneration, and/or promote neuroregeneration.
Claims21
An isolated prom-1 peptide derived from a prominin-1, wherein said peptide has regenerative activity, and wherein the peptide does not include a full-length prominin-1.
Dependencies are inferred from the claim text.