Fusion peptide designed to reduce plaque bacteria and yeast in the oral cavity
AssigneeRutgers, The State University of New Jersey
InventorsDaniel H. Fine, Kabilan Velliyagounder
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Abstract
The present invention relates generally to dental diseases, caries and periodontal disease. More specifically, the invention relates to Lactoferrin and PAK fusion peptides (PAK-LF), along with therapeutic, diagnostic and research uses for these polypeptides. The present invention also provides methods of treating dental diseases, caries and periodontal disease.
Claims28
A composition for inhibiting bacterial growth in the oral cavity comprising a fusion peptide comprising:
- i. a lysine form of a Lactoferrin polypeptide or a functionally equivalent peptide molecule thereof;
- and
- ii. a PAK polypeptide or a functionally equivalent peptide molecule thereof.
(canceled)
-15. (canceled)
A composition for inhibiting bacterial growth in the oral cavity comprising the fusion peptide of claim 24.
A fusion peptide having SEQ ID NO. 5, or a functionally equivalent peptide molecule thereof.
A nucleic acid encoding an amino acid comprising SEQ ID NO. 5.
-27. (canceled)
-36. (canceled)
Dependencies are inferred from the claim text.