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US 2014/0193925 A1Published application
Biosensors
AssigneeMassachusetts Institute of Technology
InventorsDhiman Bhattacharyya, Karen K. Gleason
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Abstract
A chemiresistive biosensor for detecting an analyte can include a high specific surface area substrate conformally coated with a conductive polymer, and a binding reagent immobilized on the conductive polymer, wherein the binding reagent has a specific affinity for the analyte. The conductive polymer can be deposited on a substrate by oCVD.
Claims30
A chemiresistive biosensor configured to detect an analyte comprising:
- a high specific surface area substrate conformally coated with a conductive polymer;
- and
- a binding reagent immobilized on the conductive polymer, wherein the binding reagent has a specific affinity for the analyte.
A method of detecting an analyte, comprising:
- contacting a sample suspected of containing the analyte with a chemiresistive biosensor comprising:
- a high specific surface area substrate conformally coated with a conductive polymer;
- and a binding reagent immobilized on the conductive polymer;
- wherein the binding reagent has a specific affinity for the analyte.
1 more element
A method of making a sensor configured to detect an analyte, comprising:
- providing a high specific surface area substrate;
- coating a conductive polymer conformally on the high specific surface area substrate;
- and
- covalently linking a binding reagent to the conductive polymer, wherein the binding reagent has a specific affinity for the analyte.
1 more element
Dependencies are inferred from the claim text.