Loading patent…
AssigneeES Cell International PTE Ltd.
InventorsBruce Paul Davidson, Ralph Eberhard Graichen, Robert Zweigerdt, Xiuqin Xu, Christine Lindsay Mummery, William Sun
Estimating the term…
The present invention relates to the induction of differentiation in human embryonic stem (hES) cells to cardiomyocytes and factors such as prostaglandin I2 (PGI2), Fgf 9, Bmp6, Bmp4, Scf, Igf2, and insulin that influence the process of differentiation to cardiomyocytes. Media that is appropriate for the induction of differentiation of cardiomyocytes from hES cells is also provided wherein the media contains these factors. Genes that are upregulated in the process of cardiomyocyte differentiation are also provided.
-34. (canceled)
A cell culture media comprising a prostaglandin or an analog or functional equivalent thereof and a cardiac progenitor cell.
A cell culture media free of insulin and comprising PGI2.
Dependencies are inferred from the claim text.