Back to results
US 2014/0193841 A1Published application
Fluorogenic semiconductor nanocrystals
AssigneeLife Technologies Corporation
InventorsEric Welch, David Bussian, Michael Ignatius, Lawrence Greenfield
Life of this patent
Estimating the term…
Abstract
Fluorogenic semiconductor nanocrystals and compositions thereof are provided herein, including kits, assay systems and methods for their preparation and use.
Claims30
A fluorogenic semiconductor nanocrystal, comprising:
- a fluorescent semiconductor nanocrystal:
- and
- a quencher group associated with the semiconductor nanocrystal, wherein the fluorescent semiconductor nanocrystal in the absence of the quencher group has an initial fluorescence intensity (F0), and the fluorogenic semiconductor nanocrystal has a quenched fluorescence intensity (FQ), wherein FQ/F0 is less than about 1.0.
-11. (canceled)
A composition, comprising:
- a population of fluorogenic semiconductor nanocrystals according to claim 11;
- and
- an aqueous or organic medium or a solid support, wherein each nanocrystal is associated with the support, if present.
-22. (canceled)
(canceled)
(canceled)
(canceled)
-40. (canceled)
-59. (canceled)
Dependencies are inferred from the claim text.