Complex sets of mirnas as non-invasive biomarkers for kidney cancer

A method for diagnosing and/or prognosing of kidney cancer comprising the steps of:

• (i) determining an expression profile of a set comprising at least two miRNAs representative for kidney cancer in a body fluid sample from a subject, and
• (ii) comparing said expression profile to a reference, wherein the comparison of said expression profile to said reference allows for the diagnosis and/or prognosis of kidney cancer,
• wherein the nucleotide sequences of the miRNAs comprised in the set are selected from the group consisting of SEQ ID NO:
• 1 to 465, a fragment thereof, and a sequence having at least 80% sequence identity thereto.