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US 2014/0193799 A1Published application
Microfabricated artificial lung assist device, and methods of use and manufacture thereof
AssigneeThe Charles Start Draper Laboratory, Inc.
InventorsJeffrey T. Borenstein, Joseph L. Charest, James Ching-Ming Hsiao, Tatiana Kniazeva
Life of this patent
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Abstract
The invention provides systems and methods for exchanging gas in an oxygenator device, and methods for preparing and using such oxygenator devices. The systems and methods can be used to transfer oxygen to blood to assist lung function in a patient.
Claims20
1-40. (canceled)
An extracorporeal membrane oxygenator device, comprising a plurality of bi-layer structures arranged in a stack, each bi-layer structure comprising:
- a first polymer layer defining a plurality of blood flow channels within a surface thereof, wherein at least a subset of the plurality of blood flow channels each have a plurality of ribs running along at least a portion of their respective lengths;
- a second polymer layer defining a plurality of gas flow channels within a surface thereof, wherein the second polymer layer is aligned with the first polymer layer such that the plurality of gas flow channels overlap the plurality of blood flow channels;
- and
- a gas permeable membrane coupled between the surface of the first polymer layer and the surface of the second polymer layer and supported by the plurality of ribs included in the subset of the plurality of blood flow channels.
1 more element
A method for transferring a gas to a liquid, the method comprising:
- providing a microfluidic device, the microfluidic device comprising:
- a first polymer layer defining a plurality of blood flow channels within a surface thereof, wherein at least a subset of the plurality of blood flow channels each have a plurality of ribs running along at least a portion of their respective lengths;
- a second polymer layer defining a plurality of gas flow channels within a surface thereof, wherein the second polymer layer is aligned with the first polymer layer such that the plurality of gas flow channels overlap the plurality of blood flow channels;
- and
- a gas permeable membrane coupled between the surface of the first polymer layer and the surface of the second polymer layer and supported by the plurality of ribs included in the subset of the plurality of blood flow channels;
- flowing blood through the plurality of blood flow channels defined in the first polymer layer;
- and
- flowing oxygen through the plurality of gas flow channels defined in the second polymer layer.
5 more elements
Dependencies are inferred from the claim text.