Foam Prepared From Nanoemulsions And Uses

A foamable oil in water nano emulsion composition comprising:

• (a) a nano oil globule system, comprising substantially of sub-micron oil globules;
• (b) about 0.1% to about 5% by weight of at least one stabilizing agent, selected from the group consisting of
• i. a non-ionic surfactant,
• ii. an ionic surfactant, and
• iii. a polymeric agent;
• and
• (c) water;
• wherein the oil, stabilizer and water are selected to provide a composition that is substantially homogenous and resistant to aging;
• wherein the composition prior to addition of propellant is translucent with a blue tint;
• wherein if the composition is contained in a pressurized container and further comprises a liquefied hydrocarbon gas propellant at a concentration of about 3% to about 35% by weight of the total composition it is substantially flowable and provides a breakable foam upon release, which is thermally stable, yet breaks under sheer force;
• and
• wherein the bubble size of the resultant foam is significantly greater than the bubble size of the resultant foam from a composition with the same ingredients which has not been subject to nano processing.

A method of promoting the penetration of an active agent into the surface layers of the skin and mucosal membranes, comprising:

• apply a foamable composition to the surface layers of a stem or mucosal membrane, the foamable composition comprising:
• (a) a nano oil globule system, comprising substantially of sub-micron oil globules;
• (b) about 0.1% to about 5% by weight of at least one stabilizing agent, selected from the group consisting of
• i. a non-ionic surfactant,
• ii. an ionic surfactant, and
• iii. a polymeric agent;
• and
• (c) water;
• wherein the oil, stabilizer and water are selected to provide a composition that is substantially homogenous and resistant to aging;
• wherein the composition prior to addition of propellant is translucent with a blue tint;
• wherein if the composition is contained in a pressurized container and further comprises a liquefied hydrocarbon gas propellant at a concentration of about 3% to about 35% by weight of the total composition it is substantially flowable and provides a breakable foam upon release, which is thermally stable, yet breaks under sheer force;
• and
• wherein the bubble size of the resultant foam is significantly greater than the bubble size of the resultant foam from a composition with the same ingredients which has not been subject to nano processing.