Intrabuccally rapidly disintegrating tablet and a production method of the tablets

A method of producing an intrabuccally rapidly disintegrating tablet, said intrabuccally rapidly disintegrating tablet comprising:

• a sugar alcohol or saccharide in the form of primary particles having an average particle size of not more than 30 μm;
• an active ingredient;
• and
• one or more disintegrants selected from the group consisting of crosspovidone, cross carmellose sodium, low substituted hydroxypropylcellulose, and a mixture thereof, said method comprising the steps of:
• (a) mixing a powder material comprising the sugar alcohol or saccharide, said active ingredient and said one or more disintegrants;
• (b) granulating the mixture of step (a), thereby producing granulated material having a predetermined particle size;
• and
• (c) compressing the granulated mixture into an intrabuccally rapidly disintegrating tablet.