Compositions comprising tnf-specific antibodies for oral delivery
AssigneeAvaxia Biologics, Incorporated
InventorBarbara S. Fox
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Abstract
In accordance with the invention, the development and use of antibodies within the digestive tract is provided. Antibodies are described that are used to treat disorders associated with altered permeability of the digestive tract. Antibodies are described with increased stability within the environment of the digestive tract. Antibodies are described with enhanced permeability to a compromised digestive tract.
Claims5
A composition for oral delivery to a human patient comprising anti-TNF antibodies, wherein upon oral administration of the antibodies to the digestive tract of the patient, the antibodies are therapeutically effective to treat inflammatory bowel disease in the patient, and wherein the antibodies are present in the composition at a dosage of about 1 mg per day to about 1 gram per day.
Dependencies are inferred from the claim text.