Method for integrating large scale biological data with imaging
AssigneeAlgeomics, LLC
InventorMichael D. Kuo
Life of this patent
Estimating the term…
Abstract
There is disclosed a method of extracting large scale biological, biochemical or molecular information about an index disease, biological state, or systems from imaging by correlating the imaging features associated with said disease, state or system with corresponding large scale biological data.
Claims46
A method of predicting a possible prognosis, treatment outcome, or diagnosis of a patient comprising:
- a) imaging said patient;
- b) identifying radiophenotype(s) in said images of said patient;
- and
- c) diagnosing or predicting a treatment outcome or prognosis of said patient based on the presence and/or absence of said radiophenotype(s).
A method of identifying radiophenotype(s) of a biological state of a specimen comprising;
- a) Providing large scale biological, biochemical or molecular data of said biological state;
- b) Imaging said specimen;
- and
- c) Correlating the information contained in said images with said large scale biological, biochemical or molecular information.
A method of determining the likelihood of an adverse reaction to a drug candidate in a patient comprising:
- a) Determining the pharmacogenomic or pharmacogenetic profile of the drug candidate on a population;
- b) Determining adverse responder population to said drug candidate;
- c) Image said adverse responder population;
- d) Imaging said patient;
- e) Correlate the image of said adverse responder population to imaging said patient;
- and
- f) Determining whether said patient is a candidate for said drug therapy based on said correlation.
A method of determining whether a patient having a disease state is a candidate for a drug therapy comprising:
- a) Determining the pharmacogenomic or pharmacogenetic profile of the drug candidate on a population;
- b) Determining responder population to said drug candidate;
- c) Image said responder population;
- d) Imaging said patient;
- e) Correlate the image of said responder population to imaging said patient;
- and
- f) Determining whether said patient is a candidate for said drug therapy based on said correlation.
A tangible medium of expression comprising data related to radiophenotype, radiogenotype, radiogenomic association, or association map.
Dependencies are inferred from the claim text.