Metal-citrate transporter antigen from streptomyces coelicolor and uses thereof
AssigneeSyracuse University
InventorsRobert P. Doyle, Joshua J. Lensbouer
Life of this patent
Estimating the term…
Abstract
The present invention relates to an isolated antigen from Streptomyces coelicolor that is useful for developing, inter alia, vaccines against pathogenic bacteria of humans and animals. The present invention also relates to vaccines and antibodies developed using the isolated antigen. The present invention also relates to methods of using the antigen, vaccines, and antibodies of the present invention to detect, treat, and prevent infection and diseases associated with pathogenic bacteria.
Claims10
An isolated antibody or antigen-binding fragment thereof that specifically binds with high affinity to an antigen, wherein said antigen comprises:
- (a) an isolated metal-citrate transporter from Streptomyces coelicolor;
- or
- (b) an isolated immunogenic polypeptide fragment of said metal-citrate transporter, wherein said immunogenic fragment retains an antigenic activity of said metal-citrate transporter.
Dependencies are inferred from the claim text.