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OwnerYongzhang LUO, Wei ZHUO +3inventors
InventorsYongzhang LUO, Wei ZHUO, Lin JIA, Yan FU, Guodong CHANG
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The present invention provides a method for inhibiting lymphangiogenesis in a subject, comprising administering a therapeutically effective amount of a CXCR4 inhibitor and/or a CXCL12 inhibitor to the subject. The invention further provides a method for inhibiting tumor lymphatic metastasis in a cancer patient, comprising administering to the subject (a) a therapeutically effective amount of a CXCR4 inhibitor and/or a CXCL12 inhibitor, in combination with (b) a therapeutically effective amount of a VEGF-C inhibitor and/or a VEGF-D inhibitor and/or a VEGFR-3 inhibitor.
Use of a CXCR4 inhibitor and/or a CXCL12 inhibitor in the manufacture of a preparation for inhibiting lymphangiogenesis in a subject.
Use of a CXCR4 inhibitor and/or a CXCL12 inhibitor in the preparation of a medicament for inhibiting tumor lymphatic metastasis in a cancer patient.
Use of (a) a CXCR4 inhibitor and/or a CXCL12 inhibitor, and (b) a VEGF-C inhibitor and/or a VEGF-D inhibitor and/or a VEGFR-3 inhibitor, in the preparation of a medicament for inhibiting tumor lymphatic metastasis in a cancer patient.
A pharmaceutical composition for inhibiting tumor lymphatic metastasis in a cancer patient, comprising:
A kit for inhibiting tumor lymphatic metastasis in a cancer patient, comprising:
Dependencies are inferred from the claim text.