Epitopes of IL-17A and IL-17F and Antibodies Specific Thereto
AssigneeUCB Pharma S.A.
InventorsThomas Allen Ceska, Alistar James Henry, Jiye Shi
Life of this patent
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Abstract
The present invention relates neutralising epitopes of IL-17A and IL-17F and antibodies which bind those epitopes. The present invention also relates to the therapeutic uses of the antibody molecules and methods for producing them.
Claims8
(canceled)
A chimeric or humanised antibody that specifically binds an epitope of human IL-17F, wherein the epitope comprises residues GLN71, CYS72, ILE86, ASN89, SER90 and VAL128 of SEQ ID NO:22.
A monoclonal antibody that specifically binds an epitope of human IL-17F, wherein the epitope comprises residues GLN71, CYS72, ILE86, ASN89, SER90 and VAL128 of SEQ ID NO:22 and wherein the monoclonal antibody additionally binds IL-17A.
Dependencies are inferred from the claim text.