Regenerative Nanosensor Devices
AssigneeYale University
InventorsMark A. Reed, Xuexin Duan, Nitin Rajan
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Abstract
The present invention provides a regenerative nanosensor device for the detection of one or more analytes of interest. In certain embodiments, the device comprises a nanostructure having a reversible functionalized coating comprising a supramolecular assembly. Controllable and selective disruption of the assembly promotes desorption of at least part of the reversible functionalized coating thereby allowing for reuse of the regenerative device.
Claims38
A regenerative nanosensor device comprising a nanostructure forming an electrically conducting pathway between at least a first contact and a second contact, the nanostructure surface having a reversible coating comprising a reversible functionalized supramolecular assembly.
A method of manufacturing a regenerative nanosensor device comprising:
- providing a device comprising a nanostructure forming an electrically conducting pathway between at least a first contact and a second contact;
- and
- forming a reversible coating comprising a reversible functionalized supramolecular assembly atop the surface of the nanostructure.
A method of replacing a receptor molecule functionalized on the nanostructure of a regenerative nanosensor device comprising:
- providing a regenerative nanosensor device comprising a nanostructure forming an electrically conducting pathway between at least a first contact and a second contact, the nanostructure surface having a first coating comprising a reversible functionalized supramolecular assembly comprising a first receptor molecule;
- and
- disrupting the supramolecular assembly of the first coating to induce the selective removal of at least one layer of the first coating, thereby forming an unfunctionalized nanostructure.
Dependencies are inferred from the claim text.