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US 2014/0155844 A1Published application
Antimicrobial barrier device
AssigneeCook Medical Technologies LLC
InventorsAndrew P. Isch, Steven J. Charlebois
Life of this patent
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Abstract
The invention relates to an antimicrobial barrier device and methods of manufacture. The antimicrobial barrier comprises one or more antimicrobial drugs that inhibit biofilm formation and bacterial and/or fungal growth. The antimicrobial barrier is suited for use with insertable devices (e.g., catheters) to reduce the incidence of infection at and around the insertion site.
Claims20
An antimicrobial barrier device comprising:
- a soft durometer silicone body comprising one or more directly incorporated antimicrobial drugs selected from the group consisting of an antifungal agent and an antibacterial agent, the soft durometer silicone body being substantially resistant to microbial colonization thereon, and having
- a) a first surface adapted to conform to a treatment area;
- and
- b) a hole extending therethrough, the hole being adapted to receive and seal to an insertable medical device.
1 more element
A kit comprising:
- an insertable medical device;
- and
- a soft durometer silicone body comprising one or more directly incorporated antimicrobial drugs selected from the group consisting of an antifungal agent and an antibacterial agent, the soft durometer silicone body being substantially resistant to microbial colonization thereon, and having
- a) a first surface adapted to conform to a treatment area;
- and
- b) a hole extending therethrough, the hole being adapted to receive and seal to an insertable medical device.
3 more elements
A method of manufacturing an antimicrobial barrier by directly incorporating an antimicrobial drug into a soft durometer silicone body comprising the steps of:
- a) dissolving one or more antimicrobial drugs in one or more solvents to provide a dissolved one or more antimicrobial drugs;
- b) mixing the dissolved one or more antimicrobial drugs with a first silicone elastomer to provide a first silicone elastomer mixture;
- c) evaporation of the one or more solvents from the first silicone elastomer mixture to provide a second silicone elastomer mixture;
- d) mixing the second silicone elastomer mixture with a second silicone elastomer to provide a third silicone elastomer mixture;
- e) transferring the third silicone elastomer mixture to a mold;
- and
- f) curing the third silicone elastomer mixture in the mold.
4 more elements
Dependencies are inferred from the claim text.