Therapeutic delivery system

A nasal dilator comprising:

• an elongated, flexible substrate having a peripheral edge, a central longitudinal axis, a longitudinal length and transverse ends;
• a resinous resilient layer comprising three resilient portions, said resinous resilient layer bonded to said elongated, flexible substrate to provide a gentle expanding force to a nasal wall tissue when said dilator is adhesively attached to a wearer's nose, said three resilient portions including a first resilient portion disposed longitudinally between said transverse ends, a second resilient portion, having a shorter longitudinal length than said first resilient portion and located laterally from said first resilient portion, and a central bridging resilient portion having a shorter longitudinal length than said second resilient portion, connecting said first and second resilient portions;
• and
• a pressure sensitive adhesive layer disposed on the entire bottom surface of said dilator.

A nasal dilator for substantially preventing a nasal wall tissue of a nose from drawing in during breathing, comprising

• an elongated, flexible substrate having a peripheral edge, a central longitudinal axis, a pair of longitudinal sides, a pair of transverse end regions, and top and bottom surfaces thereon;
• a resilient layer comprising three resilient portions, said resilient layer bonded to said elongated, flexible substrate to provide a gentle expanding force to said nasal wall tissue when said dilator is adhesively attached to said nose;
• a first of said resilient portions having a pair of transverse free ends, said first of said resilient portions disposed longitudinally along said elongated, flexible substrate from a first of said pair of transverse end regions of said substrate to a second of said pair of transverse end regions of said substrate, a second of said resilient portions disposed laterally on said elongated, flexible substrate from said first resilient portion, and a third of said resilient portions disposed to bridge said first and second resilient portions;
• and
• a pressure sensitive adhesive layer disposed on said bottom surface of said dilator, including on the central region of said dilator for attachment to the bridge of the wearer's nose.

A nasal dilator comprising:

• an elongated, flexible substrate having a longitudinal length, a central region, and a pair of transverse ends;
• a resilient layer having a plurality of resilient portions therein, said resilient layer bonded to said elongated, flexible substrate to provide an expanding force to a nasal wall tissue when said dilator is adhesively attached to a wearer's nose, said plurality of resilient portions comprising a first and a second resilient portion disposed between said transverse ends of said elongated flexible substrate and a bridging portion connecting said first and second portions together, said first and second resilient portions separated from one another at each of said pair of transverse ends;
• and
• a pressure sensitive adhesive layer disposed on said bottom surface of said dilator, including on the central region of the dilator for attachment to the bridge of the wearer's nose.