Intestinal brake inducing intraluminal therapeutic substance eluting devices and methods

A method of inducing satiety comprising

• a. implanting a stent within a lumen of a gastrointestinal tract;
• b. retaining a portion of chyme that flows by the stent within a body of said stent;
• and
• c. re-releasing the retained chyme from said stent into the gastrointestinal tract at a predetermined rate slower than a rate caused by natural peristalsis.

A method of producing satiety comprising:

• a. surgically accessing a gastrointestinal tract of a patient;
• b. splitting said tract into a first lumen for passage of nutrients and a second lumen;
• c. implanting a device within said second lumen;
• and
• d. eluting a satiety inducing substance from the device into the gastrointestinal tract.