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US 2014/0155769 A1Published application
Devices, Systems, and Methods for Pulmonary Arterial Hypertension (PAH) Assessment and Treatment
AssigneeCardioMEMS, Inc.
InventorsJason White, Ralph Jordan, John Erik Moore, Jay Yadav
Life of this patent
Estimating the term…
Abstract
Provided herein are devices, systems, and methods for assessing, treating, and for developing new treatments for pulmonary arterial hypertension (PAH) using pulmonary artery pressure (PAP) values and/or cardiac output (CO) estimates.
Claims60
A method of evaluating progress of pulmonary arterial hypertension (PAH) in a subject, or an outcome in a subject having PAH, comprising:
- (a) obtaining a pulmonary artery pressure waveform from the subject;
- (b) determining one or more pulmonary artery pressure (PAP) values from the pulmonary artery waveform;
- (c) estimating cardiac output (CO) using the pulmonary artery pressure waveform;
- (d) comparing one or more of the PAP values and one or more of the CO estimates to standard PAP and CO values respectively;
- and
- (e) using the comparisons of PAP and CO to monitor the PAH progression or outcome in the subject.
3 more elements
A method for evaluating treatment of a subject having PAH, comprising:
- (a) administering an agent to the subject;
- (b) obtaining a pulmonary artery pressure waveform from the subject;
- (c) determining one or more pulmonary artery pressure (PAP) values from the pulmonary artery waveform;
- (d) estimating cardiac output (CO) using the pulmonary artery pressure waveform;
- (e) comparing one or more of the PAP values and one or more of the CO estimates to standard PAP and CO values respectively;
- and
- (f) using the comparisons of PAP and CO to monitor the effect of the administered agent on the PAH condition in the subject.
4 more elements
A method for evaluating treatment of a subject having PAH, comprising:
- (a) administering an agent to the subject;
- (b) obtaining a pulmonary artery pressure waveform from the subject;
- (c) determining one or more pulmonary artery pressure (PAP) values from the pulmonary artery waveform;
- (d) comparing one or more of the PAP values to a standard PAP value;
- and
- (e) using the comparison of PAP to monitor the effect of the administered agent on the PAH condition in the subject.
3 more elements
A method for evaluating treatment of a subject having PAH, comprising:
- (a) administering an agent to the subject;
- (b) obtaining a pulmonary artery pressure waveform from the subject;
- (c) estimating cardiac output (CO) using the pulmonary artery pressure waveform;
- (d) comparing one or more of the estimated CO values to a standard CO value;
- and
- (e) using the comparison of CO to monitor the effect of the administered agent on the PAH condition in the subject.
3 more elements
Dependencies are inferred from the claim text.