Transdermal device
AssigneeUniversity of Strathclyde
InventorPatricia Connolly
Life of this patent
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Abstract
A transdermal device (10) for sensing one or more analytes in a biological fluid, the device (10) comprising a liquid or gel layer (14); a sensor (18) located in the liquid or gel layer (14) for sensing analyte in the gel layer and an outer layer (16) that is adapted to bind with or trap the one or more analytes of interest, wherein the device (10) is arranged so that in use the analyte is continuously drawn out of the liquid or gel (14) and into the outer layer (16) and the analyte concentration as a function of position across the gel/liquid has a defined profile.
Claims32
A transdermal device for sensing one or more analytes in a biological fluid, the device comprising a liquid or gel layer;
- a sensor located in the liquid or gel layer for sensing analyte in the liquid or gel layer and an outer layer adapted to bind with or trap the one or more analytes of interest, wherein the device is arranged so that in use the analyte is continuously drawn out of the liquid or gel and into the outer layer and the analyte concentration as a function of position across the gel/liquid has a defined profile.
A device as claimed in, wherein the binding/trapping agent comprises as charcoal or porous carbon.
A method for determining in vivo concentration of an analyte using a transdermal device, the method comprising:
- measuring skin impedance;
- measuring flux of an analyte through the skin and
- using the measured impedance and flux to determine internal concentration of the analyte.
Dependencies are inferred from the claim text.