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AssigneeDong-A St Co., Ltd.
InventorsMiwon Son, Tae Ho Lee, Sang Zin Choi, Nam Joon Baek, Kang Ro Lee, Ki Hyun Kim, Soon Hoe Kim
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The present invention relates to a novel quinoline derivative compound, an optical isomer thereof, a pharmaceutically acceptable salt thereof, and a hydrate or a solvate thereof. The novel quinoline derivative compound, the optical isomer thereof, the pharmaceutically acceptable salt thereof, and the hydrate or the solvate thereof accelerates gastrointestinal movement, and thus can effectively prevent or treat gastrointestinal motility disorders.
A quinoline derivative compound represented by the following Chemical Formula 1, an optical isomer thereof, a pharmaceutically acceptable salt thereof, or a hydrate or solvate thereof:
A method for preparing a compound represented by the following Chemical Formula 1, an optical isomer thereof, a pharmaceutically acceptable salt thereof, and a hydrate or solvate thereof, comprising reacting a compound represented by the following Chemical Formula 3 or an optical isomer thereof with a compound represented by the following Chemical Formula 4 or an optical isomer thereof in presence of a base:
A pharmaceutical composition for prevention or treatment of a gastrointestinal motility disorder, comprising a novel quinoline derivative compound represented by the following Chemical Formula 1, an optical isomer thereof, a pharmaceutically acceptable salt thereof, or a hydrate or solvate thereof:
Dependencies are inferred from the claim text.