Novel compounds

A compound represented by formula (I):

• wherein
• R1 is hydrogen, (C1-C4) alkyl, or —SO2(C1-C4)alkyl;
• R2 is aryl or a 5 to 11 membered heteroaryl, wherein said aryl or heteroaryl is optionally substituted by 1 to 3 groups at each occurrence independently selected from the group consisting of halogen, (C1-C4)haloalkyl, hydroxy, —SO2NR8R9, —CN, —NR10SO2R11, (C1-C4) alkyl, and (C1-C4) alkoxy, wherein said (C1-C4) alkyl or (C1-C4) alkoxy are optionally substituted by one (C3-C7) cycloalkyl group, and wherein
• R8 is hydrogen or (C1-C6) alkyl;
• R9 is hydrogen or (C1-C6) alkyl;
• R10 is hydrogen or (C1-C6) alkyl;
• R11 is hydrogen or (C1-C6 alkyl;
• Z is a bond or a divalent radical selected from the group consisting of —(CH2)m—, —S—, —S(O)—, —S(O2)—, a group —C(O)—, and a group [1]-(CH2)m—OC(O)-[2] wherein [1] and [2] represent, respectively the point of attachment of group Z to phenyl ring and to the nitrogen atom, and m is an integer ranging from 1 to 4;
• L1 is:
• a bond,
• —(CH2)p—,
• [3]-(CH2)p—O-[4]
• [3]-(CH2)p—NR10—(CH2)t-[4]
• [3]-(CH2)p—OC(O)-[4]
• [3]-(CH2)p—NR10C(O)-[4]
• [3]-(CH2)p—NR10S(O2)-[4] or
• [3]-(CH2)p—S(O2)—N(R10)-[4]
• wherein [3] and [4] represent, respectively the point of attachment of group L1 to the carbonyl group and to the phenyl ring, and wherein
• R10 is as described above,
• p is an integer ranging from 1 to 4 and
• t is an integer ranging from 1 to 4
• each R3 is independently hydrogen, halogen, (C1-C4) haloalkyl, hydroxy, aminocarbonyl, di-(C1-C4) alkylaminocarbonyl, —SO2NR12R13, —CN, —NR14SO2R15, —(CH2)m—NR14SO2R15—, (C1-C4) alkyl, or (C1-C4) alkoxy, wherein said (C1-C4) alkyl or (C1-C4) alkoxy are optionally substituted by one (C3-C7) cycloalkyl group, m is as described above and
• R12 is hydrogen or (C1-C6) alkyl;
• R13 is hydrogen or (C1-C6) alkyl;
• R14 is hydrogen or (C1-C6) alkyl;
• R15 is hydrogen or (C1-C6) alkyl;
• q is an integer ranging from 1 to 3;
• R4 and R5 are the same of different and are independently:
• H;
• (C3-C7) cycloalkylcarbonyl;
• (C1-C6) alkyl, optionally substituted by one or more substituents selected from (C3-C7) cycloalkyl and (C5-C7) cycloalkenyl;
• (C1-C6) haloalkyl;
• (C3-C7) cycloalkyl;
• (C5-C7) cycloalkenyl;
• (C2-C6) alkenyl;
• or
• (C2-C6) alkynyl;
• or R4 and R5, together with the interconnecting atoms, form a 2,2-difluoro-1,3-dioxolane ring of formula (r) fused to the phenyl moiety which bears groups —OR4 and —OR5, wherein asterisks indicate carbon atoms shared with said phenyl ring:
• each R6 is independently CN, NO2, CF3, or a halogen atom;
• n is 0 or an integer ranging from 1 to 3;
• A is a nitrogen containing group which is:
• a group (a) which is —(CH2)s—NR16R17 wherein s is an integer ranging from 1 to 4 and R16 and R17 are independently hydrogen or (C1-C4) alkyl;
• or
• a group (b) which is a saturated monocyclic, bicyclic or tricyclic heterocyclic ring system optionally substituted by one or two groups R18 which are at each occurrence independently selected from (C1-C4) alkyl and benzyl,
• or an N-oxide on the pyridine ring, a deuterated derivative, or a pharmaceutically acceptable salt thereof.