Novel compounds

A compound represented by formula (I):

• wherein
• W is aryl or heteroaryl;
• each R1 is independently hydrogen, halogen, (C1-C4) alkyl, (C1-C4) alkoxy, (C1-C4) haloalkyl, hydroxy, —SO2NR6R7, —CN, —NR8SO2R9, —NR6R7, —CONR6R7, or —NR8COR9, and wherein said (C1-C4) alkyl is optionally substituted by one or more groups selected from the group consisting of (C3-C7) cycloalkyl, hydroxyl, and —NR6R7 and said (C1-C4) alkoxy is optionally substituted by one or more halogen atoms or (C3-C7) cycloalkyl groups, and
• wherein,
• R6 is hydrogen or (C1-C6) alkyl;
• R7 is hydrogen or (C1-C6) alkyl;
• R8 is hydrogen or (C1-C6) alkyl;
• R9 is hydrogen or (C1-C6) alkyl;
• n is an integer ranging from 1 to 3;
• each R2 is independently hydrogen, halogen, (C1-C4) alkyl, (C1-C4) alkoxy, (C1-C4)haloalkyl, hydroxy, —SO2NR10R11, —CN, or —NR12SO2R13, and wherein said (C1-C4) alkyl and (C1-C4) alkoxy are optionally substituted by one (C3-C7) cycloalkyl group,
• R10 is hydrogen or (C1-C6) alkyl;
• R11 is hydrogen or (C1-C6) alkyl;
• R12 is hydrogen or (C1-C6) alkyl;
• R13 is hydrogen or (C1-C6) alkyl;
• m is an integer ranging from 1 to 3;
• p is zero or 1;
• L1 is a group (CH2)t wherein t is 0 or an integer ranging from 1 to 3;
• L2 is:
• (CH2)q wherein q is an integer ranging from 1 to 3,
• divalent ortho-benzyl (o-C6H4—CH2—),
• divalent meta-benzyl (m-C6H4—CH2—),
• divalent para-benzyl (p-C6H4—CH2—),
• divalent ortho-methyleneoxy-benzyl (o-CH2—O—C6H4—CH2—),
• divalent meta-methyleneoxy-benzyl (m-CH2—O—C6H4—CH2—), or
• divalent para-methylenoxy-benzyl (p-CH2—O—C6H4—CH2—), wherein the carbon chain atom of the benzyl group is linked to the nitrogen atom and the respective aromatic carbon atom or the methylene carbon atom of the methylene oxy group is linked to the phenyl group;
• R3 and R4 are different or the same and are each independently:
• H;
• (C3-C7) cycloalkylcarbonyl;
• (C1-C6) alkyl, optionally substituted by one or more substituents selected from (C3-C7) cycloalkyl or (C5-C7) cycloalkenyl;
• (C1-C6) haloalkyl;
• (C3-C7) cycloalkyl;
• (C5-C7) cycloalkenyl;
• (C2-C6) alkenyl;
• or
• (C2-C6) alkynyl;
• or R3 and R4, together with the interconnecting atoms, form a 2,2-difluoro-1,3-dioxolane ring of formula (r) fused to the phenyl moiety which bears groups —OR3 and —OR4, wherein asterisks indicate carbon atoms shared with the phenyl ring:
• each R5 is independently CN, NO2, CF3 or a halogen atom;
• k is an integer ranging from 1 to 3;
• and
• A is a nitrogen containing group which may be:
• a group (a) which is —(CH2)s—NR14R15 wherein s is an integer ranging from 1 to 4 and R14 and R15 are independently hydrogen or (C1-C4) alkyl;
• or
• a group (b) which is a saturated monocyclic, bicyclic, or tricyclic heterocyclic ring system optionally substituted by one or two groups R16 which are at each occurrence independently (C1-C4) alkyl or benzyl;
• an N-oxide on the pyridine ring, deuterated derivative, or a pharmaceutically acceptable salt thereof.