Combination pharmaceuticals and methods thereof using proteinacious channels as treatments for medical conditions
AssigneeLoyola University of Chicago
InventorKenneth L. Byron
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Abstract
Methods and combination pharmaceuticals for treating bronchospastic medical conditions by utilizing the electrophysiology of proteinacious channels in lipid membranes of mammalian cells. The combination pharmaceuticals include at least one β-adrenergic receptor agonist, and at least one composition adapted to effect the electrophysiology of Kv7 potassium channels of a lipid membrane of an airway smooth muscle cell. The pharmaceutical may be administered to a living body in a therapeutic amount sufficient to activate the Kv7 potassium channels of an airway smooth muscle cell.
Claims17
A combination pharmaceutical comprising:
- at least one β-adrenergic receptor agonist;
- and
- at least one composition adapted to effect the electrophysiology of Kv7 potassium channels of a lipid membrane of an airway smooth muscle cell.
A method of treating a bronchospastic condition that can lead to airway obstruction in a living body, the method comprising administering a pharmaceutical to the living body in a therapeutic amount sufficient to activate the Kv7 potassium channels of an airway smooth muscle cell.
Dependencies are inferred from the claim text.