Back to results
US 2014/0155345 A1Published application
Biotinylated compounds
AssigneeRutgers, The State University of New Jersey
InventorsRoger A. Jones, Barbara L. Gaffney
Life of this patent
Estimating the term…
Abstract
The invention provides new biotinylated compounds and methods for their use.
Claims20
A compound of formula I or formula II:
- wherein:
- each B is independently
- X is (C2-C8)alkyl, (C2-C8)alkenyl or (C2-C8)alkynyl, wherein one or more carbon atoms of the (C2-C8)alkyl, (C2-C8)alkenyl or (C2-C8)alkynyl may be optionally replaced with one or more groups independently selected from O, S, C(═O) and NRa provided that the O, S or NRa are not adjacent to any other O, S or NRa, and wherein any (C2-C8)alkyl, (C2-C8)alkenyl or (C2-C8)alkynyl of X is optionally substituted with one or more groups independently selected from halogen, ORb and NRb2;
- Y is (C2-C28)alkyl, (C2-C28)alkenyl or (C2-C28)alkynyl, wherein one or more carbon atoms of the (C2-C28)alkyl, (C2-C28)alkenyl or (C2-C28)alkynyl may be optionally replaced with one or more groups independently selected from O, S, C(═O) and NRc provided that the O, S or NRc are not adjacent to any other O, S or NRc, and wherein any (C2-C28)alkyl, (C2-C28)alkenyl or (C2-C28)alkynyl of Y is optionally substituted with one or more groups independently selected from halogen, ORd and NRd2;
- W is O or S;
- each Ra is independently selected from H and (C1-C6)alkyl;
- each Rb is independently selected from H and (C1-C6)alkyl;
- each Rc is independently selected from H and (C1-C6)alkyl;
- and
- each Rd is independently selected from H and (C1-C6)alkyl;
- or a salt thereof.
8 more elements
Dependencies are inferred from the claim text.