Novel peptides and uses thereof in therapeutic methods
AssigneeTwo To Biotech Ltd.
InventorsTamara Sandler, Orly Devary
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Abstract
The invention relates to polypeptides exhibiting metabolic-modulating as well as immunomodulatory properties, nucleic acids encoding them, compositions comprising them, and methods of treating metabolic disorders and/or immune-related disorders comprising their administration and to their use in preparing pharmaceutical compositions for the treatment, amelioration, prophylaxis or delaying the onset of at least one of a metabolic disorder and an immune-related disorder.
Claims15
1-49. (canceled)
An isolated polypeptide comprising (a) the amino acid sequence set forth in SEQ ID NO:
- 1;
- (b) the amino acid sequence set forth in SEQ ID NO:
- 13;
- or (c) an amino acid sequence that is at least 80% identical to SEQ ID NO:
- 1 or SEQ ID NO:
- 13.
A method for improving glucose metabolism in a subject suffering from a glucose metabolism related disorder, said method comprising administering an effective amount of an isolated polypeptide comprising (a) the amino acid sequence set forth in SEQ ID NO:
- 1;
- (b) the amino acid sequence set forth in SEQ ID NO:
- 13;
- or (c) an amino acid sequence that is at least 80% identical to SEQ ID NO:
- 1 or SEQ ID NO:
- 13;
- or a pharmaceutical composition comprising the same.
Dependencies are inferred from the claim text.