Selectively targeted antimicrobial peptides and the use thereof

A STAMP composition comprising

• a) a targeting peptide, wherein the targeting peptide having an amino acid sequence selected from the group consisting of SEQ ID NOs 2, 5 and 10;
• b) a linker peptide, wherein one terminus of the linker peptide is linked to the targeting peptide;
• and
• c) an antimicrobial peptide, wherein the antimicrobial peptide is linked to the other terminus of the linker peptide.

A STAMP composition comprising:

• a) an antimicrobial peptide, wherein the antimicrobial peptide having an amino acid sequence selected from the group consisting of SEQ ID NOs 3, 7, and 11;
• b) a linker peptide, wherein one terminus of the linker peptide is linked to the antimicrobial peptide;
• and
• c) a targeting peptide, wherein the targeting peptide is linked to the other terminus of the linker peptide.

A STAMP composition comprising:

• a) a targeting peptide, wherein the targeting peptide having an amino acid sequence length of 4-50 amino acids;
• b) a linker peptide, wherein one terminus of the linker peptide is linked to the targeting peptide;
• c) an antimicrobial peptide, wherein the antimicrobial peptide is linked to the other terminus of the linker peptide;
• and
• d) an antibiotic.