US 2014/0154790 A1Published application

Biomolecule information analysis device

AssigneeHitachi, Ltd.

InventorsKazuo Ono, Tatsuo Nakagawa, Yoshimitsu Yanagawa, Takayuki Kawahara, Akira Kotabe, Riichiro Takemura

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Abstract

Provided is a device that, on the basis of a measurement result of a current that has a low value and a wide distribution, identifies the composition of biological molecules passing through a nanoparticle path. This biomolecule information analysis device obtains a current value by applying an electrical field to biomolecules passing through a gap between a first electrode and a second electrode, and identifies the structure of the biomolecules by integrating the current value and making a comparison with a reference value (see FIG. 1).

Claims15

Dependent claims

A biomolecule information analysis apparatus, comprising:

a first and a second electrodes forming a molecule path through which a biomolecule passes;
an electric voltage application circuit that applies an electric voltage to the first and the second electrodes when the biomolecule passes through the molecule path;
an integration circuit that integrates an electric current caused to flow by an application of an electric voltage by the electric voltage application circuit to the first and the second electrodes;
and
a comparison circuit that identifies a structure of the biomolecule by comparing an integration result of the integration circuit with a predetermined reference value.

2 more elements

Dependencies are inferred from the claim text.

Facts

Application: 14/122,206Filed 31 May 2011
Published: 5 Jun 2014
Term ends: Not estimatedThe source records don’t support an estimate.

Classification5 codes

C12Q 1/68
Measuring or testing processes involving enzymes, nucleic acids or microorganisms ; Compositions therefor; Processes of preparing such…
C12Q 1/6869
Involving nucleic acids: methods for sequencing
G01N 33/48721
By electrical means: investigating individual macromolecules, e.g. by translocation through nanopores
C12Q
Measuring or testing processes involving enzymes, nucleic acids or microorganisms

Family

US 9,725,753 B2Related patent
US 2014/0154790 A1This patent

From the US filing history. Foreign family members aren’t listed.

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