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AssigneesHirosaki University, Peptide Institute, Inc., Riken
InventorsKatsuya Yamada, Hirotaka Onoe, Tadashi Teshima, Toshihiro Yamamoto
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The purpose of the present invention is to provide a method for highly accurately detecting a cancer cell. The method of the present invention is characterized by comprising imaging with the use of a fluorescently labeled L-glucose derivative. By using the method and imaging agent according to the present invention, a high contrast between a cancer cell and a normal cell can be obtained compared with the case that imaging is conducted with the use of a fluorescently labeled D-glucose derivative. According to this method, moreover, no fasting is needed for the determination. Thus, the imaging can be quickly carried out without imposing a burden on a patient.
A method of detecting cancer cells or suspected cells, comprising the following steps:
An imaging agent for imaging a target cell by uptake of a fluorescently labeled L-glucose derivative into the target cell, wherein the agent contains an L-glucose derivative having a 7-nitrobenz-2-oxa-1,3-diazole group or its derivative as a fluorescent molecular group in the molecule.
Dependencies are inferred from the claim text.