Methods for measuring carcinoembryonic antigen
AssigneeRedPath Integrated Pathology, Inc.
InventorsSydney David Finkelstein, Sara Ann Jackson, Jamie Michelle Bleicher, Eric Matthew Gayle Ellsworth, Dennis Morgan Smith, JR.
Life of this patent
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Abstract
Disclosed herein are methods of accurately measuring carcinoembryonic antigen in a biological sample and methods of identifying and treating a mucinous cyst in a subject.
Claims63
A method of accurately measuring carcinoembryonic antigen in a biological sample, the method comprising:
- diluting the biological sample to form a diluted sample when an amylase level in the biological sample is less than a pre-determined amylase threshold between about 10,000 and about 20,000 units;
- wherein diluting the biological sample comprises diluting the biological sample with a diluent in a ratio of biological sample to diluent of between about 1:10 and about 1:50;
- and
- measuring carcinoembryonic antigen in the diluted sample.
A method of accurately measuring carcinoembryonic antigen in a biological sample, the method comprising:
- diluting the biological sample with a diluent at a ratio of biological sample to diluent of about 1:10 to about 1:50 to form a diluted biological sample, wherein the amylase level in the biological sample is greater than a pre-determined amylase threshold between about10,000 and about 20,000 units;
- measuring carcinoembryonic antigen level in the diluted biological sample;
- multiplying the carcinoembryonic antigen level by a correction factor to obtain a corrected carcinoembryonic antigen level.
A method of identifying a mucinous cyst in a subject, the method comprising:
- diluting the biological sample with a diluent when an amylase level in the biological sample is less than a pre-determined amylase threshold between about 10,000 and about 20,000 units, to form a diluted sample, wherein diluting the biological sample with a diluent comprises diluting the biological sample in a ratio of biological sample to diluent between about 1:10 and about 1:50;
- and
- measuring carcinoembryonic antigen level in the saline diluted sample;
- wherein a carcinoembryonic antigen level above a predetermined carcinoembryonic antigen level threshold in the diluted sample is indicative of a mucinous cyst.
A method of identifying a mucinous cyst in a subject, the method comprising:
- diluting the biological sample with a diluent at a ratio of biological sample to diluent of about 1:10 to about 1:50 to form a diluted biological sample, wherein the amylase levels in the biological sample are greater than a pre-determined amylase threshold between about 10,000 and about 20,000 units;
- measuring carcinoembryonic antigen level in the diluted biological sample;
- multiplying the carcinoembryonic antigen level of the diluted biological sample by a correction factor to obtain a corrected carcinoembryonic antigen level;
- and
- wherein a corrected carcinoembryonic antigen level of above a predetermined carcinoembryonic antigen threshold is indicative of a mucinous cyst.
Dependencies are inferred from the claim text.