Back to results
US 2014/0154680 A1Published application
Diagnostic, predictive and prognostic testing for cancer
AssigneeCambridge Cancer Diagnostics Limited
InventorsKai STOEBER, Gareth HAYDEN WILLIAMS
Life of this patent
Estimating the term…
Abstract
The present invention relates generally to the field of cancer. In particular, the present invention relates to cancer prognostic and treatment protocols.
Claims19
A method for determining a treatment protocol for a subject having cancer, the method comprising the in vitro steps of:
- a) assessing the level of a first biomarker selected from at least one of Mcm2 to 7 in a biological sample from the subject;
- and
- b) assessing the level of a second biomarker selected from at least one of geminin, Aurora A, Plk1 and H3S10ph in a biological sample from the subject,
- wherein the combination of the level of the first biomarker compared to a pre-determined value and the level of the second biomarker compared to a predetermined value is indicative of the treatment regimen prescribed for the subject.
1 more element
A method for predicting therapeutic treatment response of a subject having cancer, the method comprising the steps of:
- a) assessing a level of a first biomarker selected from at least one of Mcm2 to 7 in a biological sample from the subject;
- and
- b) assessing the level of a second biomarker selected from at least one of geminin, Aurora A, Plk1 and H3S10ph in a biological sample from the subject;
- wherein the combination of the level of the first biomarker compared to a pre-determined value and the level of the second biomarker compared to a predetermined value is indicative of the efficacy of the therapeutic treatment.
1 more element
A method for determining the progression of a cancer in a subject, comprising the in vitro steps of:
- a) assessing the level of a first biomarker selected from at least one of Mcm2 to 7 in a biological sample from the subject;
- and
- b) assessing the level of a second biomarker selected from at least one of geminin, Aurora A, Plk1 and H3S10ph in a biological sample from the subject,
- wherein the combination of the level of the first biomarker compared to a pre-determined value and the level of the second biomarker compared to a predetermined value is indicative of cancer progression in the subject.
1 more element
Dependencies are inferred from the claim text.