Formulas comprising highly soluble elements and vitamin for the prevention and amelioration of osteoporosis
AssigneeSinoveda Canada, Inc.
InventorYun Kau Tam
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Abstract
The present invention provides methods of producing dosage forms for formulas of elemental compositions encompassing acetate salts of calcium, magnesium and zinc along with vitamin D3. The acetate salts could be extracted from natural sources such as pearls, coral, and oyster or compounded using synthetic materials. The dosage and ratio of calcium to magnesium was estimated using in vitro and in vivo estimations. The dosage for promoting bone health and alleviation of osteoporosis is about a quarter to a third of the conventional dose.
Claims10
A method of preparing tablets comprising calcium acetate, magnesium acetate, zinc acetate and vitamin D3, the method comprises the steps of:
- (i) blending a first calcium composition comprising calcium acetate, magnesium acetate, and zinc acetate with a composition comprising vitamin D3;
- and
- (ii) blending the composition obtained from (i) with a second calcium composition comprising calcium acetate, magnesium acetate, and zinc acetate;
- (iii) performing one or more rounds of blending wherein in each blending a composition obtained from a previous step is blended with yet another calcium composition comprising calcium acetate, magnesium acetate, and zinc acetate, thereby obtaining composition comprising calcium acetate, magnesium acetate, zinc acetate and vitamin D3 for preparing tablets.
A method of preparing soft gel capsules comprising calcium acetate, magnesium acetate, zinc acetate, oil and vitamin D3, the method comprises the steps of:
- (i) dissolving vitamin D3 in oil comprising omega 3 or omega 3-6-9;
- and
- (ii) blending the composition obtained from (i) with a calcium composition comprising calcium acetate, magnesium acetate, and zinc acetate, thereby obtaining composition comprising calcium acetate, magnesium acetate, zinc acetate, oil and vitamin D3 for preparing soft gel capsules.
Dependencies are inferred from the claim text.