For injectable formulations containing asenapine and method of treatment using same
OwnerWerenfridus Adrianus Faassen, Gerardus Johannes Kemperman +1inventors
InventorsWerenfridus Adrianus Faassen, Gerardus Johannes Kemperman, Johannes Antonius van Laarhoven
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Abstract
The present invention provides a formulation comprising asenapine hemipamoate suspended particles, which formulation can be administered via a Depot provided by an IM injection of the formulation, and which depot does not display a particle-size dependent release rate. The present invention provides also methods of treatment using the same.
Claims3
1-20. (canceled)
A pharmaceutical formulation comprising an aqueous suspension of particles of crystalline Form II of asenapine hemipamoate, wherein said asenapine hemipamoate is present at a concentration of 5 wt. % or greater of the suspension, and wherein, said particles comprise less than about 10 vol % of particles having a mean diameter of less than 1 micron and have a d50-value of from about 1.5 microns to about 40 microns.
Dependencies are inferred from the claim text.