Method and computer program product for genotype classification

A method for genotype classification, the method comprising the steps of:

• a) acquiring a pair of scanned images of an SNP sample for a plurality of individuals selected from a population, wherein one image of the image pairs is associated with a first allele and the other image of the image pair is associated with a second allele of the sample,
• b) for both images of the associated scanned image pair of each sample,
• i) performing pre-processing of the image to remove scanning noises from the image,
• ii) obtaining total sample intensity information from the image,
• iii) defining a sample boundary to encompass at least a substantial part of the luminous pixels of the image,
• iv) matching said sample boundary to the image,
• v) performing a pixel-based processing of the image using the matched sample boundary in order to obtain image quality information with respect to said sample,
• c) based on said sample intensity information and said image quality information of the sample, grouping the samples into discrete clusters of different genotypes.