Imaging systems with movable scan mirrors
AssigneeComplete Genomics, Inc.
InventorsBryan P. Staker, Craig E. Uhrich
Life of this patent
Estimating the term…
Abstract
An imaging system is provided wherein a positioning stage is translated with respect to an objective lens component and a scan mirror is repositioned while a two-dimensional image is made of a biochemical site on a substrate. In an example embodiment, an imaging system comprises a camera, an objective lens component, a positioning stage, and a scan mirror controllable by a servo system that synchronizes movement of the positioning stage and the tilting of the scan mirror so that the substrate image is maintained stable during imaging of the continuously moving positioning stage.
Claims21
An imaging system comprising:
- a camera with a two dimensional electronic sensor;
- an objective lens component configured to image at least a portion of a substrate onto the two dimensional sensor of the camera to produce a two-dimensional image;
- a positioning stage configured to move in continuous motion the substrate in a first direction with respect to the objective lens component;
- and
- a scan mirror configured to tilt in continuous motion in coordination with the moving positioning stage, while the positioning stage moves the substrate in the first direction, in order to reflect light from the objective lens component to the camera while maintaining the substrate image stable at the electronic sensor.
A method for imaging at least a portion of a substrate, the method comprising:
- moving a positioning stage carrying nucleic acid targets on the substrate under an objective lens component;
- while the substrate is moving, changing angle of a scan mirror such that the substrate image that is acquired by the objective lens component is maintained still with respect to a two-dimensional electronic sensor of a camera;
- and
- recording the substrate image through the electronic sensor while the substrate is moving.
An imaging system comprising:
- an objective lens component that images an array chip containing biochemical materials onto a two-dimensional electronic sensor of a camera;
- a scan mirror, capable of angular motion, that reflects light from the objective lens component to the electronic sensor;
- and
- a positioning stage that moves the array chip with respect to the objective lens component and in coordination with the scan mirror for maintaining a stable image of the array chip at the electronic sensor during continuous movement.
Dependencies are inferred from the claim text.