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US 2014/0150534 A1Published application
Scanning non-contact surface microrheometer
AssigneeThe Regents of the University of California
InventorsMichael Dennin, Thomas Boatwright, Alexander Levine, Arthur A. Evans, Roy Shlomovitz
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Abstract
The disclosure provides non-contact microrheological methods that can measure the fluctuation of a particle in a monolayer, where the particle is hydrodynamically coupled to the monolayer. The disclosure further comprises devices to carry out the non-contact microrheological methods thereof, including Laser Tweezer devices which can study in vitro biological processes.
Claims14
A non-contact microrheological method comprising:
- measuring a particle fluctuation of a particle in or near a monolayer by using a weak laser trap in combination with a back focal plane displacement detection scheme, wherein the particle is held at a fixed depth below an air/liquid, liquid/liquid, or solid/liquid interface and its small fluctuations in a plane parallel to the monolayer surface is measured, and wherein the particle is hydrodynamically coupled to the monolayer.
Dependencies are inferred from the claim text.