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AssigneeBizen Chemical Co., Ltd.
InventorsTeruyuki Kanada, Toru Kuyama, Takahiko Hada, Takafumi Ishihara
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It is an object of the present invention to provide a leukotriene receptor antagonist that can be conveniently prepared from a natural source. The object has been achieved by finding that a marine product such as a squid phospholipid extract or an Akiami paste shrimp phospholipid extract contains the antagonists of BLT and CysLT1, which are leukotriene receptors. Therefore, the present invention provides a dietary composition and a pharmaceutical composition for inhibiting the activity of leukotriene receptors, containing a squid phospholipid extract or an Akiami paste shrimp phospholipid extract.
A method for inhibiting the activity of a leukotriene receptor, comprising a step of administering a phospholipid extract of a marine product.
A method for the prevention and/or treatment of a disease selected from the group consisting of ulcerative colitis, interstitial pneumonia, atopic dermatitis, contact-type dermatitis, psoriasis, bronchial asthma, chronic obstructive pulmonary diseases, sporadic lethal asthma and ischemic renal diseases, wherein the method comprises a step of administering a phospholipid extract of a marine product having a BLT receptor inhibitory activity.
A method for the prevention and/or treatment of a disease selected from the group consisting of bronchial asthma, bronchiolitis, allergic rhinitis, atopic dermatitis, mastocytoma and ischemic cardiac diseases, wherein the method comprises a step of administering a phospholipid extract of a marine product having a CysLT1 receptor inhibitory activity.
Dependencies are inferred from the claim text.