Pneumococcal serotypes
AssigneesThe UAB Foundation, Instituto Adolfo Lutz, FundaçãO Oswaldo Cruz
InventorsMoon H. Nahm, Jisheng Lin, Angela P. Brandao, Maria Cristina Brandileone
Life of this patent
Estimating the term…
Abstract
Disclosed is a new and emerging serotype of Streptococcus pneumoniae designated serotype 6C, and assays and monoclonal antibodies useful in identifying same. Also disclosed is a novel pneumococcal polysaccharide with the repeating unit {2) glucose 1 (1→3) glucose 2 (1→3) rhamnose (1→3) ribitol (5→phosphate}. This new serotype may be included in pneumococcal vaccines.
Claims6
An isolated culture of a bacterial strain designated Streptococcus pneumoniae 6C characterized in having a polysaccharide repeating unit {→2) glucose 1 (1→3) glucose 2 (1→3) rhamnose (1→3) ribitol (5→phosphate}.
A vaccine comprising a polysaccharide derived from the bacterial strain designated Streptococcus pneumoniae 6C having a polysaccharide repeating unit {→2) glucose 1 (1→3) glucose 2 (1→3) rhamnose (1→3) ribitol (5→phosphate}.
A vaccine comprising a purified polysaccharide having a repeating unit {→2) glucose 1 (1→3) glucose 2 (1→3) rhamnose (1→3) ribitol (5→phosphate}.
An antigen binding molecule that binds to a Streptococcus pneumoniae 6C polysaccharide repeating unit:
- {→2) glucose 1 (1→3) glucose 2 (1→3) rhamnose (1→3) ribitol (5→phosphate}.
An antigen binding molecule that differently binds to Streptococcus pneumoniae 6A and Streptococcus pneumoniae 6C.
A chemical or genetic test that differentiates for Streptococcus pneumoniae 6C.
Dependencies are inferred from the claim text.